Tenocare EF (Efavirenz 600mg, Emtricitabine 200mg, Tenofovir 300mg) Atripla generic
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Tenocare EF (Efavirenz 600mg, Emtricitabine 200mg, Tenofovir 300mg) Atripla generic buy in India at profitable price
Tenocare EF is a combination ARV for the treatment of HIV in adults. Tenocare EF consists of three active ingredients:
The drug inhibits the action of the reverse transcriptase enzyme.
Original drug: ATRIPLA (Atripla), manufactured by Merck, Bristol-Myers Squibb, Gilead Sciences.
Generic: Tenocare EF, manufactured by Aprazer Ltd.
Patients should not be resistant to any of the three components of Tenocare EF at the time of initiation of therapy. Treatment is prescribed by an infectious disease doctor with experience in treating HIV infection.
Recommendations for use
The recommended dosage of Tenocare EF is 1 tablet by mouth once every 24 hours. Do not chew, swallow whole, drink plenty of water. Should be taken before meals, as eating often increases the concentration of efavirenz, which can cause unpleasant side effects. To prevent unwanted side effects from the nervous system, the drug is recommended to be taken before bedtime.
Tenocare EF is contraindicated in patients with chronic hepatitis B, as its use can exacerbate the disease. The most common side effects when taking Tenocare EF are:
pain in the gastrointestinal tract;
rush of blood;
difficulty falling asleep;
Rarely, lactic acidosis (excessive accumulation of lactic acid in the blood due to liver damage) occurs, which can lead to pancreatitis and liver or kidney failure.
Interaction with other medicinal products
The drug is not used simultaneously with the following drugs:
herbal preparations containing St. John's wort
bepridil or ergot alkaloids
methylergonovine (competition of efavirenz for the CYP3A4 protein can lead to a decrease in the metabolism of these drugs and the appearance of serious complications or life-threatening phenomena (cardiac arrhythmia, prolonged sedation or respiratory depression).
Tenocare EF is contraindicated in some patient groups. You should seek medical advice:
if you are allergic to tenofovir, emtricitabine, or efavirenz;
in case of reactions to any other medications;
during pregnancy, trying to conceive a child or breastfeeding;
with kidney or liver diseases;
with infectious diseases, especially hepatitis B;
for mental disorders, including depression;
with bone diseases, including osteoporosis;
while taking other medications, including prescription drugs, over-the-counter drugs, dietary supplements, or herbal medications.